3,4-Difluoronitrobenzene exhibits a unique chemical structure characterized by a benzene ring substituted with two fluorine atoms at the 3 and 4 positions, along with a nitro group (-NO2) attached to the ring. This compound exhibits notable reactivity due to the electron-withdrawing nature of both the fluorine and nitro groups. The presence of these substituents induces an increase in electrophilicity, making the benzene ring more susceptible to nucleophilic attack. As a result, 3,4-difluoronitrobenzene serves as a valuable intermediate in the synthesis of various organic compounds, particularly those with medical applications.
- Its physical properties include a melting point of roughly 52 degrees Celsius and a boiling point of around 192 degrees Celsius.
- Moreover, it exhibits limited solubility in water but is soluble in common organic solvents.
The synthesis of 3,4-difluoronitrobenzene typically requires a multi-step process wherein includes the nitration of fluorobenzene followed by selective fluorination. This compound has been widely studied due to its potential applications in various fields, including pharmaceuticals, agrochemicals, and materials science.
Synthesis and Properties of 3,4-Difluoronitrobenzene
3,4-Difluoronitrobenzene is a significant role in the realm of organic synthesis due to its unique structural characteristics. The synthesis of this compound can be achieved through various routes, with a commonly employed method involving the nitration of 1,2-difluorobenzene. This reaction typically utilizes a mixture of nitric acid and sulfuric acid as the nitrating agent, yielding the desired 3,4-difluoronitrobenzene product.
The resulting compound exhibits distinct physicochemical properties that influence its reactivity and applications. Notably, the electron-withdrawing nature of the nitro group in 3,4-difluoronitrobenzene alters its electrophilicity, making it susceptible to nucleophilic attack. This property renders it a versatile building block for the synthesis of complex organic molecules.
- Moreover, the presence of fluorine atoms in the molecule contributes to its resilience and miscibility in various solvents.
CAS No. for 3,4-Difluoronitrobenzene: Identifying This Compound
When working with chemicals, accurately pinpointing them is crucial for safety and correct results. A key tool in this process is the CAS Registry Number, a unique identifier assigned to every chemical compound. For 3,4-Difluoronitrobenzene, this number is vital for ensuring you are working with the correct substance.
The CAS No. for 3,4-Difluoronitrobenzene is 105387-96-3. This numerical identifier can be used to locate information about the compound in databases and research materials. Understanding its properties, hazards, and safe handling procedures is crucial when dealing with this chemical.
Applications of 3,4-Difluoronitrobenzene in Research
3,4-Difluoronitrobenzene finds a broad spectrum of applications in research. Its unique arrangement and physical properties enable it to be utilized as a valuable precursor in the synthesis of novel organic compounds. 3 Researchers utilize 3,4-difluoronitrobenzene for its reactivity in producing new materials with desired properties. Furthermore, this compound acts as a useful tool in the study of chemical processes. Its possibilities span numerous research areas, including organic chemistry.
Safety Considerations for Handling 3,4-Difluoronitrobenzene
When working with 3,4-difluoronitrobenzene, it is vital to prioritize safety. This chemical can be hazardous if not handled properly. Always carry out procedures in a well-ventilated region and don appropriate personal protective equipment (PPE), including gloves, eye protection, and a protective smock.
Before coming into contact with 3,4-difluoronitrobenzene, meticulously review the safety information provided by the manufacturer. This resource will provide comprehensive information on potential threats, first treatment, and preservation procedures.
- Steer clear of contact with mucous membranes. In the event of exposure, promptly flush the affected area with plenty of running water for at least quarter hour.
- Store 3,4-difluoronitrobenzene in a tempered location away from flammables and hazardous compounds.
- Eliminate of 3,4-difluoronitrobenzene properly in accordance with environmental guidelines.
Spectral Characterization of 3,4-Difluoronitrobenzene
A spectral characterization of 3,4-difluoronitrobenzene is crucial for comprehending its chemical properties and potential applications.
IR|UV-Vis|NMR spectroscopy provides valuable insight into the vibrational modes, electronic transitions, and molecular structure of this compound.
The characteristic spectral features observed often be related to the presence of the nitro group, fluorine atoms, and benzene ring. Intensive spectral analysis highlights the influence of these substituents on the overall molecular structure.
This in-depth spectral characterization enhances our knowledge of DFNB and its potential role in various chemical systems.